Journal: Molecules
Article Title: 5-Alkylamino-N-phenylpyrazine-2-carboxamides: Design, Preparation, and Antimycobacterial Evaluation
doi: 10.3390/molecules25071561
Figure Lengend Snippet: Figure 2. Plot of antimycobacterial activity against Mtb H37Ra expressed as log (1/MIC [M]) and calculated lipophilicity logP. Inactive compounds had an arbitrary value of activity of 3.0.
Article Snippet: Antimycobacterial In Vitro Activity Screening Against Mycobacterium tuberculosis H37Ra, Mycobacterium smegmatis, and Mycobacterium aurum Antimycobacterial assays were performed with fast growing Mycobacterium smegmatis DSM 43465 (ATCC 607), Mycobacterium aurum DSM 43999 (ATCC 23366) from German Collection of Microorganisms and Cell Cultures (Braunschweig, Germany) and with an avirulent strain of Mycobacterium tuberculosis H37Ra ITM-M006710 (ATCC 9431) from Belgian Co-ordinated Collections of Micro-organisms.
Techniques: Activity Assay